Repeated Remote Ischemic Conditioning Reduces Doxorubicin-Induced Cardiotoxicity

Repeated Remote Ischemic Conditioning Reduces Doxorubicin-Induced Cardiotoxicity

Objectives: This study investigated the cardioprotective effect of repeated remote ischemic preconditioning (rRIC) on doxorubicin-induced cardiotoxicity in mice. Background: Doxorubicin is an effective chemotherapeutic agent for a wide range of tumor types but its use and dosing are limited by acute...

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Bibliographic Details
Main Authors: Quan He, PhD, Fangfei Wang, MD, Thomas D. Ryan, PhD, MD, Meghana Chalasani, BS, Andrew N. Redington, MD
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:JACC. CardioOncology
Subjects:
apoptosis
autophagy
cardiac function
doxorubicin
inflammation
multiorgan toxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2666087320300077

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http://www.sciencedirect.com/science/article/pii/S2666087320300077

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