Activation of regulated cell death in the lung of piglets infected with virulent PRRSV-1 Lena strain occurs earlier and mediated by cleaved Caspase-8

Activation of regulated cell death in the lung of piglets infected with virulent PRRSV-1 Lena strain occurs earlier and mediated by cleaved Caspase-8

Abstract PRRSV-1 virulent strains cause high fever, marked respiratory disease and severe lesions in lung and lymphoid organs. Regulated cell death (RCD), such as apoptosis, necroptosis and pyroptosis, is triggered by the host to interrupt viral replication eliminating infected cells, however, altho...

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Bibliographic Details
Main Authors: Jose María Sánchez-Carvajal, Inés Ruedas-Torres, Librado Carrasco, Francisco José Pallarés, Enric Mateu, Irene Magdalena Rodríguez-Gómez, Jaime Gómez-Laguna
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Veterinary Research
Subjects:
PRRSV-1
virulent strain
regulated cell death
lung
cleaved caspase-8
Online Access:https://doi.org/10.1186/s13567-020-00882-x

Internet

https://doi.org/10.1186/s13567-020-00882-x

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