Antifibrotic effect of novel neutrophil gelatinase-associated lipocalin inhibitors in cardiac and renal disease models

Antifibrotic effect of novel neutrophil gelatinase-associated lipocalin inhibitors in cardiac and renal disease models

Abstract Neutrophil gelatinase-associated lipocalin (NGAL) is involved in cardiovascular and renal diseases. Gene inactivation of NGAL blunts the pathophysiological consequences of cardiovascular and renal damage. We aimed to design chemical NGAL inhibitors and investigate its effects in experimenta...

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Bibliographic Details
Main Authors: Benjamin Bonnard, Ernesto Martínez-Martínez, Amaya Fernández-Celis, Marie Pieronne-Deperrois, Quoc-Tuan Do, Isbaal Ramos, Patrick Rossignol, Faiez Zannad, Paul Mulder, Antoine Ouvrard-Pascaud, Natalia López-Andrés, Frédéric Jaisser
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82279-0

Internet

https://doi.org/10.1038/s41598-021-82279-0

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