Intriguing Relationships Between Cancer and Systemic Sclerosis: Role of the Immune System and Other Contributors

Systemic sclerosis (SSc) is an autoimmune connective tissue disorder, characterized by multisystem involvement, vasculopathy, and fibrosis. An increased risk of malignancy is observed in SSc (including breast and lung cancers), and in a subgroup of patients with specific autoantibodies (i.e., anti-R...

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Main Authors: Alexandre Thibault Jacques Maria, Léo Partouche, Radjiv Goulabchand, Sophie Rivière, Pauline Rozier, Céline Bourgier, Alain Le Quellec, Jacques Morel, Danièle Noël, Philippe Guilpain
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03112/full