The imprinted gene Pw1/Peg3 regulates skeletal muscle growth, satellite cell metabolic state, and self-renewal

The imprinted gene Pw1/Peg3 regulates skeletal muscle growth, satellite cell metabolic state, and self-renewal

Abstract Pw1/Peg3 is an imprinted gene expressed from the paternally inherited allele. Several imprinted genes, including Pw1/Peg3, have been shown to regulate overall body size and play a role in adult stem cells. Pw1/Peg3 is expressed in muscle stem cells (satellite cells) as well as a progenitor...

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Bibliographic Details
Main Authors: Rosa Maria Correra, David Ollitrault, Mariana Valente, Alessia Mazzola, Bjorn T. Adalsteinsson, Anne C. Ferguson-Smith, Giovanna Marazzi, David A. Sassoon
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Scientific Reports
Subjects:
Satellite Cells
Myofiber Number
Skeletal Muscle Fiber Number
Maternal Allele
Mutant Muscle
Online Access:https://doi.org/10.1038/s41598-018-32941-x

Internet

https://doi.org/10.1038/s41598-018-32941-x

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