Herbal formula Huangqi Guizhi Wuwu decoction attenuates paclitaxel-related neurotoxicity via inhibition of inflammation and oxidative stress

Herbal formula Huangqi Guizhi Wuwu decoction attenuates paclitaxel-related neurotoxicity via inhibition of inflammation and oxidative stress

Abstract Background Paclitaxel-induced peripheral neuropathy (PIPN) is a challenging clinical problem during chemotherapy. Our previous work found that herbal formula Huangqi Guizhi Wuwu decoction (HGWD) could reduce oxaliplatin-induced neurotoxicity. However, its effect on PIPN remains unknown. In...

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Bibliographic Details
Main Authors: Zhangming Lv, Jiayun Shen, Xuejiao Gao, Yonglan Ruan, Jinying Ling, Rongwei Sun, Jingya Dai, Haizhen Fan, Xiaolan Cheng, Peng Cao
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Chinese Medicine
Subjects:
Huangqi Guizhi Wuwu decoction
Paclitaxel
Peripheral neuropathy
Network pharmacology
Inflammation
Oxidative stress
Online Access:https://doi.org/10.1186/s13020-021-00488-1

Internet

https://doi.org/10.1186/s13020-021-00488-1

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