Hypermethylation of TRIM59 and KLF14 Influences Cell Death Signaling in Familial Alzheimer’s Disease

Hypermethylation of TRIM59 and KLF14 Influences Cell Death Signaling in Familial Alzheimer’s Disease

Epigenetic mechanisms play an important role in the development and progression of various neurodegenerative diseases. Abnormal methylation of numerous genes responsible for regulation of transcription, DNA replication, and apoptosis has been linked to Alzheimer’s disease (AD) pathology. We have rec...

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Main Authors: Michalina Wezyk, Magdalena Spólnicka, Ewelina Pośpiech, Beata Pepłońska, Renata Zbieć-Piekarska, Jan Ilkowski, Maria Styczyńska, Anna Barczak, Marzena Zboch, Anna Filipek-Gliszczynska, Magdalena Skrzypczak, Krzysztof Ginalski, Michał Kabza, Izabela Makałowska, Maria Barcikowska-Kotowicz, Wojciech Branicki, Cezary Żekanowski
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/6918797

Internet

http://dx.doi.org/10.1155/2018/6918797

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