A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification - implications for chemoprevention

<p>Abstract</p> <p>Background</p> <p>Centrosome aberrations can cause genomic instability and correlate with malignant progression in common human malignancies such as breast and prostate cancer. Deregulation of cyclin/cyclin-dependent kinase 2 (CDK2) activity has previ...

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Bibliographic Details
Main Authors: Chatterjee Payel, Wheeler Sarah, Korzeniewski Nina, Duensing Anette, Duensing Stefan
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/153