A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification - implications for chemoprevention
<p>Abstract</p> <p>Background</p> <p>Centrosome aberrations can cause genomic instability and correlate with malignant progression in common human malignancies such as breast and prostate cancer. Deregulation of cyclin/cyclin-dependent kinase 2 (CDK2) activity has previ...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-06-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/9/1/153 |