Comparative immunogenicity of HIV-1 clade C envelope proteins for prime/boost studies.

BACKGROUND:Previous clinical efficacy trials failed to support the continued development of recombinant gp120 (rgp120) as a candidate HIV vaccine. However, the recent RV144 HIV vaccine trial in Thailand showed that a prime/boost immunization strategy involving priming with canarypox vCP1521 followed...

Full description

Bibliographic Details
Main Authors: Douglas H Smith, Peggy Winters-Digiacinto, Misrach Mitiku, Sara O'Rourke, Faruk Sinangil, Terri Wrin, David C Montefiori, Phillip W Berman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2920315?pdf=render