Model-driven identification of dosing regimens that maximize the antimicrobial activity of nitric oxide

The antimicrobial properties of nitric oxide (NO●) have motivated the design of NO●-releasing materials for the treatment and prevention of infection. The biological activity of NO● is dependent on its delivery rate, suggesting that variable antimicrobial effects can result from identical NO● payloa...

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Bibliographic Details
Main Authors: Jonathan L. Robinson, Richard V. Miller, Mark P. Brynildsen
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Metabolic Engineering Communications
Subjects:
Hmp
Online Access:http://www.sciencedirect.com/science/article/pii/S2214030114000030