Model-driven identification of dosing regimens that maximize the antimicrobial activity of nitric oxide
The antimicrobial properties of nitric oxide (NO●) have motivated the design of NO●-releasing materials for the treatment and prevention of infection. The biological activity of NO● is dependent on its delivery rate, suggesting that variable antimicrobial effects can result from identical NO● payloa...
Main Authors: | Jonathan L. Robinson, Richard V. Miller, Mark P. Brynildsen |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-12-01
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Series: | Metabolic Engineering Communications |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214030114000030 |
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