Mutation rate and efflux response of bacteria exposed to a novel antimicrobial iodo-thiocyanate complex

Objectives: Antimicrobials, at sub-lethal concentrations, can act as selectors and promoters of resistance by increasing mutation rates. We measured the rate of Escherichia coli mutation from levofloxacin (LVX) sensitivity to resistance when it was grown under the near-lethal challenge of the novel...

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Bibliographic Details
Main Authors: Lilit Tonoyan, Ruairi Friel, Vincent O’Flaherty
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716519303212