Common polymorphic inversions at 17q21.31 and 8p23.1 associate with cancer prognosis

Common polymorphic inversions at 17q21.31 and 8p23.1 associate with cancer prognosis

Abstract Background Chromosomal inversions are structural genetic variants where a chromosome segment changes its orientation. While sporadic de novo inversions are known genetic risk factors for cancer susceptibility, it is unknown if common polymorphic inversions are also associated with the progn...

Full description

Bibliographic Details
Main Authors: Carlos Ruiz-Arenas, Alejandro Cáceres, Victor Moreno, Juan R. González
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Human Genomics
Subjects:
Chromosomal inversions
Cancer prognosis
DNA methylation
Genetic epidemiology
Gene expression
Online Access:http://link.springer.com/article/10.1186/s40246-019-0242-2

Internet

http://link.springer.com/article/10.1186/s40246-019-0242-2

Similar Items