Long Non-Coding RNA LINC00152 Regulates Self-Renewal of Leukemia Stem Cells and Induces Chemo-Resistance in Acute Myeloid Leukemia

Long Non-Coding RNA LINC00152 Regulates Self-Renewal of Leukemia Stem Cells and Induces Chemo-Resistance in Acute Myeloid Leukemia

Relapse of acute myeloid leukemia (AML) has a very poor prognosis and remains a common cause of treatment failure in patients with this disease. AML relapse is partially driven by the chemoresistant nature of leukemia stem cells (LSCs), which remains poorly understood, and our study aimed at elucida...

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Bibliographic Details
Main Authors: Chunhong Cui, Yan Wang, Wenjie Gong, Haiju He, Hao Zhang, Wei Shi, Hui Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
leukemia stem cells
LINC00152
poly (ADP-ribose) polymerase 1
chemo-resistance
leukemia
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.694021/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.694021/full

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