Lipoprotein Lipase Is a Feature of Alternatively-Activated Microglia and May Facilitate Lipid Uptake in the CNS During Demyelination

Lipoprotein Lipase Is a Feature of Alternatively-Activated Microglia and May Facilitate Lipid Uptake in the CNS During Demyelination

Severe demyelinating disorders of the central nervous system (CNS) such as multiple sclerosis (MS), can be devastating for many young lives. To date, the factors resulting in poor remyelination and repair are not well understood, and reparative therapies that benefit MS patients have yet to be devel...

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Bibliographic Details
Main Authors: Kimberley D. Bruce, Sachi Gorkhali, Katherine Given, Alison M. Coates, Kristen E. Boyle, Wendy B. Macklin, Robert H. Eckel
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
lipoprotein lipase (LPL)
microglia
multiple sclerosis
myelination
lipid metabolism
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2018.00057/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2018.00057/full

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