RNAi-Mediated Silencing of Catalase Gene Promotes Apoptosis and Impairs Proliferation of Bovine Granulosa Cells under Heat Stress

RNAi-Mediated Silencing of Catalase Gene Promotes Apoptosis and Impairs Proliferation of Bovine Granulosa Cells under Heat Stress

Heat stress in dairy cattle is recognized to compromise fertility by altering the functions of ovarian follicle-enclosed cells, e.g., oocyte and granulosa cells (GCs). Catalase is an antioxidant enzyme that plays a significant role in cellular protection against oxidative damage by the degradation o...

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Bibliographic Details
Main Authors: Adnan Khan, Muhammad Zahoor Khan, Jinhuan Dou, Saqib Umer, Huitao Xu, Abdul Sammad, Hua-Bin Zhu, Yachun Wang
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Animals
Subjects:
bovine granulosa cells
catalase silencing
heat stress
oxidative stress
apoptosis
cell proliferation
Online Access:https://www.mdpi.com/2076-2615/10/6/1060

Internet

https://www.mdpi.com/2076-2615/10/6/1060

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