Increased C-X-C Motif Chemokine Ligand 12 Levels in Cerebrospinal Fluid as a Candidate Biomarker in Sporadic Amyotrophic Lateral Sclerosis

Increased C-X-C Motif Chemokine Ligand 12 Levels in Cerebrospinal Fluid as a Candidate Biomarker in Sporadic Amyotrophic Lateral Sclerosis

Sporadic amyotrophic lateral sclerosis (sALS) is a fatal progressive neurodegenerative disease affecting upper and lower motor neurons. Biomarkers are useful to facilitate the diagnosis and/or prognosis of patients and to reveal possible mechanistic clues about the disease. This study aimed to ident...

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Bibliographic Details
Main Authors: Pol Andrés-Benito, Mònica Povedano, Raúl Domínguez, Carla Marco, Maria J. Colomina, Óscar López-Pérez, Isabel Santana, Inês Baldeiras, Sergio Martínez-Yelámos, Inga Zerr, Franc Llorens, Joaquín Fernández-Irigoyen, Enrique Santamaría, Isidro Ferrer
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
amyotrophic lateral sclerosis
cerebrospinal fluid
proteomics
biomarkers
CXCL12
CXCR4
Online Access:https://www.mdpi.com/1422-0067/21/22/8680

Internet

https://www.mdpi.com/1422-0067/21/22/8680

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