Proteomic Characterization, Biodistribution, and Functional Studies of Immune-Therapeutic Exosomes: Implications for Inflammatory Lung Diseases

Proteomic Characterization, Biodistribution, and Functional Studies of Immune-Therapeutic Exosomes: Implications for Inflammatory Lung Diseases

Dendritic cell (DC)-derived exosomes (DC EXO), natural nanoparticles of endosomal origin, are under intense scrutiny in clinical trials for various inflammatory diseases. DC EXO are eobiotic, meaning they are well-tolerated by the host; moreover, they can be custom-tailored for immune-regulatory or...

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Bibliographic Details
Main Authors: Mahmoud Elashiry, Ranya Elsayed, Mohamed M. Elashiry, Mohammad H. Rashid, Roxan Ara, Ali S. Arbab, Ahmed R. Elawady, Mark Hamrick, Yutao Liu, Wenbo Zhi, Rudolf Lucas, Jose Vazquez, Christopher W. Cutler
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
exosomes
lung diseases
immune therapy
COVID-19
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.636222/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.636222/full

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