Glucocorticoids Inhibit MUC5AC Production Induced by Transforming Growth Factor-α in Human Respiratory Cells

Glucocorticoids Inhibit MUC5AC Production Induced by Transforming Growth Factor-α in Human Respiratory Cells

Background: Mucus hypersecretion from airway epithelium is a characteristic feature of severe asthma. Glucocorticoids (GCs) may suppress mucus production and diminish the harmful airway obstruction. We investigated the ability of GCs to suppress mRNA expression and protein synthesis of a gene encodi...

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Bibliographic Details
Main Authors: Satoru Takami, Takahisa Mizuno, Takato Oyanagi, Hiromi Tadaki, Tomoko Suzuki, Kazuhiro Muramatsu, Takumi Takizawa, Hirokazu Arakawa
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Allergology International
Subjects:
asthma
glucocorticoids
mucin
transcription
viral infection
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015302410

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http://www.sciencedirect.com/science/article/pii/S1323893015302410

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