Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on Its <i>N</i>-Glycosylation

Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on Its <i>N</i>-Glycosylation

NKp30 is one of the main human natural killer (NK) cell activating receptors used in directed immunotherapy. The oligomerization of the NKp30 ligand binding domain depends on the length of the C-terminal stalk region, but our structural knowledge of NKp30 oligomerization and its role in signal trans...

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Bibliographic Details
Main Authors: Ondřej Skořepa, Samuel Pazicky, Barbora Kalousková, Jan Bláha, Celeste Abreu, Tomáš Ječmen, Michal Rosůlek, Alexander Fish, Arthur Sedivy, Karl Harlos, Jan Dohnálek, Tereza Skálová, Ondřej Vaněk
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
NK cell
NKp30
B7-H6
glycosylation
oligomerization
Online Access:https://www.mdpi.com/2072-6694/12/7/1998

Internet

https://www.mdpi.com/2072-6694/12/7/1998

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