Hinokitiol Exerts Anticancer Activity through Downregulation of MMPs 9/2 and Enhancement of Catalase and SOD Enzymes: In Vivo Augmentation of Lung Histoarchitecture

Hinokitiol Exerts Anticancer Activity through Downregulation of MMPs 9/2 and Enhancement of Catalase and SOD Enzymes: In Vivo Augmentation of Lung Histoarchitecture

Melanoma is extremely resistant to chemotherapy and the death rate is increasing hastily worldwide. Extracellular matrix promotes the migration and invasion of tumor cells through the production of matrix metalloproteinase (MMP)-2 and -9. Evidence has shown that natural dietary antioxidants are capa...

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Bibliographic Details
Main Authors: Chien-Hsun Huang, Thanasekaran Jayakumar, Chao-Chien Chang, Tsorng-Harn Fong, Shing-Hwa Lu, Philip Aloysius Thomas, Cheuk-Sing Choy, Joen-Rong Sheu
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Molecules
Subjects:
hinokitiol
melanoma
MMPs
antioxidant enzymes
histology
elastic fiber
Online Access:http://www.mdpi.com/1420-3049/20/10/17720

Internet

http://www.mdpi.com/1420-3049/20/10/17720

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