Proteinaceous Regulators and Inhibitors of Protein Tyrosine Phosphatases

Proteinaceous Regulators and Inhibitors of Protein Tyrosine Phosphatases

Proper control of the phosphotyrosine content in signal transduction proteins is essential for normal cell behavior and is lost in many pathologies. Attempts to normalize aberrant tyrosine phosphorylation levels in disease states currently involve either the application of small compounds that inhib...

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Bibliographic Details
Main Authors: Wiljan Hendriks, Annika Bourgonje, William Leenders, Rafael Pulido
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Molecules
Subjects:
biologics
PDZ domain
protein inhibitors
protein tyrosine kinases
protein–protein interaction
regulation of activity
signal transduction
Online Access:http://www.mdpi.com/1420-3049/23/2/395

Internet

http://www.mdpi.com/1420-3049/23/2/395

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