A dynamic view of trauma/hemorrhage-induced inflammation in mice: principal drivers and networks.

Complex biological processes such as acute inflammation induced by trauma/hemorrhagic shock/ (T/HS) are dynamic and multi-dimensional. We utilized multiplexing cytokine analysis coupled with data-driven modeling to gain a systems perspective into T/HS.Mice were subjected to surgical cannulation trau...

Full description

Bibliographic Details
Main Authors: Qi Mi, Gregory Constantine, Cordelia Ziraldo, Alexey Solovyev, Andres Torres, Rajaie Namas, Timothy Bentley, Timothy R Billiar, Ruben Zamora, Juan Carlos Puyana, Yoram Vodovotz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3091861?pdf=render