Intake levels of dietary long-chain PUFAs modify the association between genetic variation in FADS and LDL-C[S]

Polymorphisms of the FA desaturase (FADS) gene cluster have been associated with LDL, HDL, and triglyceride concentrations. Because FADS converts α-linolenic acid (ALA) and linoleic acid into PUFAs, we investigated the interaction between different PUFA intakes and the FADS polymorphism rs174547 (T&...

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Bibliographic Details
Main Authors: S. Hellstrand, E. Sonestedt, U. Ericson, B. Gullberg, E. Wirfält, B. Hedblad, M. Orho-Melander
Format: Article
Language:English
Published: Elsevier 2012-06-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520317119