C323 of SR-BI is required for SR-BI-mediated HDL binding and cholesteryl ester uptake[S]

Scavenger receptor BI (SR-BI) is an HDL receptor. It binds HDL and mediates the uptake of cholesteryl ester from HDL. Early studies have pointed out that the extracellular domain of SR-BI is critical for SR-BI-mediated cholesteryl ester uptake. However, the extracellular loop of SR-BI is large: it c...

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Bibliographic Details
Main Authors: Ling Guo, Min Chen, Zhiqing Song, Alan Daugherty, Xiang-An Li
Format: Article
Language:English
Published: Elsevier 2011-12-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520408314