Diabetic kidney disease in FVB/NJ Akita mice: temporal pattern of kidney injury and urinary nephrin excretion.

Akita mice are a genetic model of type 1 diabetes. In the present studies, we investigated the phenotype of Akita mice on the FVB/NJ background and examined urinary nephrin excretion as a marker of kidney injury. Male Akita mice were compared with non-diabetic controls for functional and structural...

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Main Authors: Jae-Hyung Chang, Seung-Yeol Paik, Lan Mao, William Eisner, Patrick J Flannery, Liming Wang, Yuping Tang, Natalie Mattocks, Samy Hadjadj, Jean-Michel Goujon, Phillip Ruiz, Susan B Gurley, Robert F Spurney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3319540?pdf=render