Investigation of Programmed Cell Death-1 (PD-1) Gene Variations at Positions PD1.3 and PD1.5 in Iranian Patients with Non-small Cell Lung Cancer

Investigation of Programmed Cell Death-1 (PD-1) Gene Variations at Positions PD1.3 and PD1.5 in Iranian Patients with Non-small Cell Lung Cancer

Background: Tumor cells express PD-1 ligands to bind PD-1 on immune cells and escape immune responses. In the present study, we aimed to investigate whether single nucleotide polymorphisms at positions PD1.3 (+7146, rs11568821) G/A, and PD1.5 (+7785 C/T, rs2227981) may be considered risk factors...

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Bibliographic Details
Main Authors: Zahra Pirdelkhosh, Tohid Kazemi, Mohammad Reza Haghshenas, Mohammad Ali Ghayumi, Nasrollah Erfani
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2018-01-01
Series:Middle East Journal of Cancer
Subjects:
NSCLC
PD-1
Gene variation
Single nucleotide polymorphisms (SNP)
Online Access:http://mejc.sums.ac.ir/index.php/mejc/article/view/795/335

Internet

http://mejc.sums.ac.ir/index.php/mejc/article/view/795/335

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