Brusatol, a Nrf2 Inhibitor Targets STAT3 Signaling Cascade in Head and Neck Squamous Cell Carcinoma

Brusatol, a Nrf2 Inhibitor Targets STAT3 Signaling Cascade in Head and Neck Squamous Cell Carcinoma

STAT3 is a latent transcription factor that plays a vital role in the transmission of extracellular signal from receptors to the nucleus. It has been regarded as a master transcription factor due to its role in the regulation of a broad spectrum of genes, which can contribute to oncogenesis. Persist...

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Bibliographic Details
Main Authors: Jong Hyun Lee, Shobith Rangappa, Chakrabhavi Dhananjaya Mohan, Basappa, Gautam Sethi, Zhi-Xiu Lin, Kanchugarakoppal S. Rangappa, Kwang Seok Ahn
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Biomolecules
Subjects:
brusatol
stat3 inhibitor
apoptosis
hnscc
Online Access:https://www.mdpi.com/2218-273X/9/10/550

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https://www.mdpi.com/2218-273X/9/10/550

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