In-depth characterization of viral isolates from plasma and cells compared with plasma circulating quasispecies in early HIV-1 infection.

In-depth characterization of viral isolates from plasma and cells compared with plasma circulating quasispecies in early HIV-1 infection.

BACKGROUND: The use of in vitro models to unravel the phenotypic characteristics of circulating viral variants is key to understanding HIV-1 pathogenesis but limited by the availability of primary viral isolates from biological samples. However, overall in vivo genetic variability of HIV-1 within a...

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Bibliographic Details
Main Authors: Judith Dalmau, Francisco M Codoñer, Itziar Erkizia, Maria Pino, Christian Pou, Roger Paredes, Bonaventura Clotet, Javier Martinez-Picado, Julia G Prado
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3290612?pdf=render

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http://europepmc.org/articles/PMC3290612?pdf=render

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