Evolutionary triplet models of structured RNA.
The reconstruction and synthesis of ancestral RNAs is a feasible goal for paleogenetics. This will require new bioinformatics methods, including a robust statistical framework for reconstructing histories of substitutions, indels and structural changes. We describe a "transducer composition&quo...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-08-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2725318?pdf=render |