Stearoly-CoA desaturase 1 differentiates early and advanced dengue virus infections and determines virus particle infectivity.

Stearoly-CoA desaturase 1 differentiates early and advanced dengue virus infections and determines virus particle infectivity.

Positive strand RNA viruses, such as dengue virus type 2 (DENV2) expand and structurally alter ER membranes to optimize cellular communication pathways that promote viral replicative needs. These complex rearrangements require significant protein scaffolding as well as changes to the ER chemical com...

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Bibliographic Details
Main Authors: Rebekah C Gullberg, J Jordan Steel, Venugopal Pujari, Joel Rovnak, Dean C Crick, Rushika Perera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6114894?pdf=render

Internet

http://europepmc.org/articles/PMC6114894?pdf=render

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