Gamma Oryzanol Alleviates High-Fat Diet-Induced Anxiety-Like Behaviors Through Downregulation of Dopamine and Inflammation in the Amygdala of Mice

Gamma Oryzanol Alleviates High-Fat Diet-Induced Anxiety-Like Behaviors Through Downregulation of Dopamine and Inflammation in the Amygdala of Mice

BackgroundA high-fat diet (HFD) can induce obesity and metabolic disorders that are closely associated with cognitive impairments, and the progression of several psychiatric disorders such as anxiety. We have previously demonstrated the anxiolytic-like effect of Gamma oryzanol (GORZ) in chronic rest...

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Bibliographic Details
Main Authors: Salina Akter, Kazi Rasel Uddin, Hiroyuki Sasaki, Shigenobu Shibata
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
high-fat diet
γ-oryzanol
anxiety
dopamine
amygdala
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00330/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.00330/full

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