Repurposing the yellow fever vaccine for intratumoral immunotherapy

Repurposing the yellow fever vaccine for intratumoral immunotherapy

Abstract Live 17D is widely used as a prophylactic vaccine strain for yellow fever virus that induces potent neutralizing humoral and cellular immunity against the wild‐type pathogen. 17D replicates and kills mouse and human tumor cell lines but not non‐transformed human cells. Intratumoral injectio...

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Bibliographic Details
Main Authors: Maria Angela Aznar, Carmen Molina, Alvaro Teijeira, Inmaculada Rodriguez, Arantza Azpilikueta, Saray Garasa, Alfonso R Sanchez‐Paulete, Luna Cordeiro, Iñaki Etxeberria, Maite Alvarez, Sergio Rius‐Rocabert, Estanislao Nistal‐Villan, Pedro Berraondo, Ignacio Melero
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:EMBO Molecular Medicine
Subjects:
17D
cancer immunotherapy
intratumoral administration
virotherapy
yellow fever vaccine
Online Access:https://doi.org/10.15252/emmm.201910375

Internet

https://doi.org/10.15252/emmm.201910375

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