Dynamic Changes in the Global Transcriptome and MicroRNAome Reveal Complex miRNA-mRNA Regulation in Early Stages of the Bi-Directional Development of Echinococcus granulosus Protoscoleces

Dynamic Changes in the Global Transcriptome and MicroRNAome Reveal Complex miRNA-mRNA Regulation in Early Stages of the Bi-Directional Development of Echinococcus granulosus Protoscoleces

BackgroundCystic echinococcosis is a life-threatening disease caused by the larval stages of the dog tapeworm Echinococcus granulosus. Protoscoleces (PSCs) of this worm have the ability of bi-directional development to either larval cysts or strobilar adult worms. However, the molecular mechanisms u...

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Bibliographic Details
Main Authors: Yun Bai, Zhuangzhi Zhang, Lei Jin, Yongqiang Zhu, Li Zhao, Baoxin Shi, Jun Li, Gang Guo, Baoping Guo, Donald P. McManus, Shengyue Wang, Wenbao Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Microbiology
Subjects:
Echinococcus granulosus
protoscoleces
microRNA
transcriptome
differential expression
bi-directional development
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00654/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00654/full

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