The bacterial fimbrial tip acts as a mechanical force sensor.

There is increasing evidence that the catch bond mechanism, where binding becomes stronger under tensile force, is a common property among non-covalent interactions between biological molecules that are exposed to mechanical force in vivo. Here, by using the multi-protein tip complex of the mannose-...

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Bibliographic Details
Main Authors: Pavel Aprikian, Gianluca Interlandi, Brian A Kidd, Isolde Le Trong, Veronika Tchesnokova, Olga Yakovenko, Matt J Whitfield, Esther Bullitt, Ronald E Stenkamp, Wendy E Thomas, Evgeni V Sokurenko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3091844?pdf=render