Aggravated brain injury after neonatal hypoxic ischemia in microglia-depleted mice

Aggravated brain injury after neonatal hypoxic ischemia in microglia-depleted mice

Abstract Background Neuroinflammation plays an important role in neonatal hypoxic-ischemic encephalopathy (HIE). Although microglia are largely responsible for injury-induced inflammatory response, they play beneficial roles in both normal and disease states. However, the effects of microglial deple...

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Bibliographic Details
Main Authors: Shunichiro Tsuji, Elena Di Martino, Takeo Mukai, Shoko Tsuji, Takashi Murakami, Robert A. Harris, Klas Blomgren, Ulrika Åden
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Neuroinflammation
Subjects:
Microglia
Hypoxic-ischemic encephalopathy
Neonate
Ischemic stroke
Online Access:http://link.springer.com/article/10.1186/s12974-020-01792-7

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http://link.springer.com/article/10.1186/s12974-020-01792-7

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