An angiogenic role for adrenomedullin in choroidal neovascularization.

PURPOSE: Adrenomedullin (ADM) has been shown to take part in physiological and pathological angiogenesis. The purpose of this study was to investigate whether ADM signaling is involved in choroidal neovascularization (CNV) using a mouse model. METHODS AND RESULTS: CNV was induced by laser photocoagu...

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Bibliographic Details
Main Authors: Susumu Sakimoto, Hiroyasu Kidoya, Motohiro Kamei, Hisamichi Naito, Daishi Yamakawa, Hirokazu Sakaguchi, Taku Wakabayashi, Kohji Nishida, Nobuyuki Takakura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3592925?pdf=render