Claudin-2-dependent paracellular channels are dynamically gated

Claudin-2-dependent paracellular channels are dynamically gated

Intercellular tight junctions form selectively permeable barriers that seal the paracellular space. Trans-tight junction flux has been measured across large epithelial surfaces, but conductance across individual channels has never been measured. We report a novel trans-tight junction patch clamp tec...

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Bibliographic Details
Main Authors: Christopher R Weber, Guo Hua Liang, Yitang Wang, Sudipto Das, Le Shen, Alan S L Yu, Deborah J Nelson, Jerrold R Turner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-11-01
Series:eLife
Subjects:
tight junction
epithelium
ion channel
patch clamp
barrier function
intestine
Online Access:https://elifesciences.org/articles/09906

Internet

https://elifesciences.org/articles/09906

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