A Randomized Phase II Study of S-1 Adjuvant Chemotherapy With or Without Hochu-ekki-to, a Japanese Herbal Medicine, for Stage II/III Gastric Cancer: The KUGC07 (SHOT) Trial

Objectives: A multicenter randomized phase II study was conducted to evaluate the effects of Hochu-ekki-to (TJ-41) for reducing adverse reactions and increasing compliance with S-1 adjuvant therapy for advanced gastric cancer.Methods: The eligibility criteria were pathological stage II/III after R0...

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Main Authors: Hiroshi Okabe, Yousuke Kinjo, Kazutaka Obama, Hisahiro Hosogi, Hiroaki Hata, Yoshito Asao, Hideki Harada, Dai Manaka, Atsushi Itami, Satoshi Teramukai, Yoshiharu Sakai
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Oncology
Subjects:
S-1
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00294/full