Some <it>ABCA3 </it>mutations elevate ER stress and initiate apoptosis of lung epithelial cells

<p>Abstract</p> <p>Background</p> <p>ABCA3 transporter (ATP-binding cassette transporter of the A subfamily) is localized to the limiting membrane of lamellar bodies, organelles for assembly and storage of pulmonary surfactant in alveolar epithelial type II cells (AECII...

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Bibliographic Details
Main Authors: Holzinger Andreas, Schams Andrea, Woischnik Markus, Hector Andreas, Kaltenborn Eva, Weichert Nina, Kern Sunčana, Griese Matthias
Format: Article
Language:English
Published: BMC 2011-01-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/12/1/4