Statins decrease lung inflammation in mice by upregulating tetraspanin CD9 in macrophages.

Statins decrease lung inflammation in mice by upregulating tetraspanin CD9 in macrophages.

Tetraspanins organize protein complexes in tetraspanin-enriched membrane microdomains that are distinct from lipid rafts. Our previous studies suggested that reduction in the levels of tetraspanins CD9 and CD81 may be involved in the progression of inflammatory lung diseases, especially COPD. To sea...

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Bibliographic Details
Main Authors: Yingji Jin, Isao Tachibana, Yoshito Takeda, Ping He, Sujin Kang, Mayumi Suzuki, Hanako Kuhara, Satoshi Tetsumoto, Kazuyuki Tsujino, Toshiyuki Minami, Takeo Iwasaki, Kaori Nakanishi, Satoshi Kohmo, Haruhiko Hirata, Ryo Takahashi, Koji Inoue, Izumi Nagatomo, Hiroshi Kida, Takashi Kijima, Mari Ito, Hideyuki Saya, Atsushi Kumanogoh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3767596?pdf=render

Internet

http://europepmc.org/articles/PMC3767596?pdf=render

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