Characterization of functional antibody and memory B-cell responses to pH1N1 monovalent vaccine in HIV-infected children and youth.

We investigated immune determinants of antibody responses and B-cell memory to pH1N1 vaccine in HIV-infected children.Ninety subjects 4 to <25 years of age received two double doses of pH1N1 vaccine. Serum and cells were frozen at baseline, after each vaccination, and at 28 weeks post-immunizatio...

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Bibliographic Details
Main Authors: Donna J Curtis, Petronella Muresan, Sharon Nachman, Terence Fenton, Kelly M Richardson, Teresa Dominguez, Patricia M Flynn, Stephen A Spector, Coleen K Cunningham, Anthony Bloom, Adriana Weinberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4364897?pdf=render