Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains.

Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains.

BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) has a broad spectrum of disease states ranging from mild steatosis characterized by an abnormal retention of lipids within liver cells to steatohepatitis (NASH) showing fat accumulation, inflammation, ballooning and degradation of hepatocytes, and...

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Main Authors: Vikash Pandey, Marc Sultan, Karl Kashofer, Meryem Ralser, Vyacheslav Amstislavskiy, Julia Starmann, Ingrid Osprian, Christina Grimm, Hendrik Hache, Marie-Laure Yaspo, Holger Sültmann, Michael Trauner, Helmut Denk, Kurt Zatloukal, Hans Lehrach, Christoph Wierling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4210132?pdf=render

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http://europepmc.org/articles/PMC4210132?pdf=render

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