Transcriptional Changes during Naturally Acquired Zika Virus Infection Render Dendritic Cells Highly Conducive to Viral Replication

Summary: Although dendritic cells are among the human cell population best equipped for cell-intrinsic antiviral immune defense, they seem highly susceptible to infection with the Zika virus (ZIKV). Using highly purified myeloid dendritic cells isolated from individuals with naturally acquired acute...

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Bibliographic Details
Main Authors: Xiaoming Sun, Stephane Hua, Hsiao-Rong Chen, Zhengyu Ouyang, Kevin Einkauf, Samantha Tse, Kevin Ard, Andrea Ciaranello, Sigal Yawetz, Paul Sax, Eric S. Rosenberg, Mathias Lichterfeld, Xu G. Yu
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717317540