Loss of G2A promotes macrophage accumulation in atherosclerotic lesions of low density lipoprotein receptor-deficient mice

Loss of G2A promotes macrophage accumulation in atherosclerotic lesions of low density lipoprotein receptor-deficient mice

Lysophosphatidylcholine (LPC) is considered a major proatherogenic component of oxidized low density lipoprotein based on its proinflammatory actions in vitro. LPC stimulates macrophage and T-cell chemotaxis via the G protein-coupled receptor G2A and may thus promote inflammatory cell infiltration d...

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Bibliographic Details
Main Authors: Brian W. Parks, Ginger P. Gambill, Aldons J. Lusis, Janusz H.S. Kabarowski
Format: Article
Language:English
Published: Elsevier 2005-07-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
lysophosphatidylcholine
T cells
chemotaxis
apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520329916

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http://www.sciencedirect.com/science/article/pii/S0022227520329916

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