Synthesis and QSAR Study of Novel 6-Chloro-3-(2-Arylmethylene-1-methylhydrazino)-1,4,2-benzodithiazine 1,1-Dioxide Derivatives with Anticancer Activity

A series of new 6-chloro-3-(2-arylmethylene-1-methylhydrazino)-1,4,2-benzodithiazine 1,1-dioxide derivatives were effectively synthesized from N-methyl-N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazines. The intermediate compounds as well as the products, were evaluated for their cytotoxic e...

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Bibliographic Details
Main Authors: Jarosław Sławiński, Beata Żołnowska, Zdzisław Brzozowski, Anna Kawiak, Mariusz Belka, Tomasz Bączek
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/4/5754