Ratio of mitochondrial to nuclear DNA affects contamination estimates in ancient DNA analysis

Ratio of mitochondrial to nuclear DNA affects contamination estimates in ancient DNA analysis

Abstract In the last decade, ancient DNA research has grown rapidly and started to overcome several of its earlier limitations through Next-Generation-Sequencing (NGS). Among other advances, NGS allows direct estimation of sample contamination from modern DNA sources. First NGS-based approaches of e...

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Bibliographic Details
Main Authors: Anja Furtwängler, Ella Reiter, Gunnar U. Neumann, Inga Siebke, Noah Steuri, Albert Hafner, Sandra Lösch, Nils Anthes, Verena J. Schuenemann, Johannes Krause
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Scientific Reports
Subjects:
Contamination Estimates
Petrous Bone
Skeletal Elements
mtDNA Contamination
Mapping Stringencies
Online Access:https://doi.org/10.1038/s41598-018-32083-0

Internet

https://doi.org/10.1038/s41598-018-32083-0

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