GNG5 Controls the Number of Apical and Basal Progenitors and Alters Neuronal Migration During Cortical Development

GNG5 Controls the Number of Apical and Basal Progenitors and Alters Neuronal Migration During Cortical Development

Cortical development is a very complex process in which any temporal or spatial alterations can give rise to a wide range of cortical malformations. Among those malformations, periventricular heterotopia (PH) is characterized by clusters of neurons that do not migrate to the correct place. Cerebral...

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Bibliographic Details
Main Authors: Ane Cristina Ayo-Martin, Christina Kyrousi, Rossella Di Giaimo, Silvia Cappello
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Molecular Biosciences
Subjects:
GNG5
human cortical development
basal progenitor cells
neuronal migration
cerebral organoids
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2020.578137/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2020.578137/full

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