Imaging cyclic AMP changes in pancreatic islets of transgenic reporter mice.
Cyclic AMP (cAMP) and Ca(2+) are two ubiquitous second messengers in transduction pathways downstream of receptors for hormones, neurotransmitters and local signals. The availability of fluorescent Ca(2+) reporter dyes that are easily introduced into cells and tissues has facilitated analysis of the...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-05-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2330161?pdf=render |