Imaging cyclic AMP changes in pancreatic islets of transgenic reporter mice.

Imaging cyclic AMP changes in pancreatic islets of transgenic reporter mice.

Cyclic AMP (cAMP) and Ca(2+) are two ubiquitous second messengers in transduction pathways downstream of receptors for hormones, neurotransmitters and local signals. The availability of fluorescent Ca(2+) reporter dyes that are easily introduced into cells and tissues has facilitated analysis of the...

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Bibliographic Details
Main Authors: Joung Woul Kim, Craig D Roberts, Stephanie A Berg, Alejandro Caicedo, Stephen D Roper, Nirupa Chaudhari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2330161?pdf=render

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